High Throughput Screening with Multiphoton Excitation

Nootropic Medicinal Plants; Evaluating Potent Formulation By Novelestic High throughput Pharmacological Screening (HTPS) Method

The principle of this method was to screen the pharmacological activity of six prepared polyphyto formulations by using high throughput screening method for their nootropic action. The study was performed in three stages using one, two and three animals, respectively in a group. Test formulations were given p.o daily at the dose of 50 and 100 mg/kg body weight. The test formulations were compar...

A High - Throughput Screening Approach

The high-throughput search described in this paper takes advantage of multiple levels of parallelism, from coarse to fine-grained. Roughly speaking, fine-grained parallelism is exploited by allocating one core (of which modern graphics hardware have many; and their number is exponentially growing over the years) to one or more virtual neurons, while coarse-scale parallelism is achieved by alloc...

High-throughput screening flows along.

mouse medulloblastomas, which are cerebel-lar tumors that, in humans, occur primarily between 5 and 10 years of age 7. Because the tumors spread through the CNS, treatment consists of surgical resection, radiation to the entire brain and spine, and chemotherapy and, as a consequence, leaves survivors with debili-tating learning and neuroendocrine hormonal deficiencies. A potential implication o...

Virtual screening: a real screening complement to high-throughput screening.

Virtual screening is being routinely used as an integral part of today's hit-identification strategies for, on one hand, prioritizing large corporate screening collections and, on the other hand, to extend the scope of screening to external databases. A brief description of the essential elements required for virtual screening and an application example to the identification of agonist hits for...

Keywords : NSOM , SNOM , fluorescence spectroscopy , multiphoton excitation